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Antimicrobial/Antiviral agents

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Business
Life Science
ETC
혈액순환개선제
Ambactam Inj. 750 mg
Category
ETC
Indication(s)·Usage
    • 1. Effective strains
      *Staphylococcus aureus, *Staphylococcus epidermidis, Streptococcus pneumoniae, Enterococcus faecalis, Streptococcus pyogenes (group A-beta hemolytic), Streptococcus viridans, *Hemophilus influenzae, *Parainfluenza *Moraxella catarrhalis, *Escherichia coli, *Klebsiella, *Proteus mirabilis, Proteus vulgaris, Providencia rettgeri, Morganella morganii, Enterobacter, *Neisseria gonorrhoeae, *Bacteroidosis (Including Bacteroides fragilis), Providencia stuartii
      (*: Including beta-lactamase producing strains)

    • 2. Indication(s)
      • - Upper and lower respiratory infection (including otitis media, epiglottitis, sinusitis)
      • - Bacterial pneumonia
      • - Urinary tract infections and pyelonephritis
      • - Intra-Abdominal Infections (including peritonitis, cholecystitis, endometritis, pelvic cellulitis)
      • - Bacterial septicemia
      • - Skin and skin structure infections
      • - Bone and joint infection
      • - Gonorrhea
      • - Prophylaxis of postoperative infection in abdominal, gynecological, and orthopaedic surgery
Effective components
Ampicillin Sodium (KP) 500 mg
Sulbactam Sodium (KP) 250 mg

Active ingredient(s) and Contents

  • Effective components

    • Ampicillin Sodium (KP) 500 mg
      Sulbactam Sodium (KP) 250 mg

  • Other

Dosage and administration

    • * Injection method
      • ㆍ Injection: Inject slowly for at least 10 to 15 minutes, and inject for 15 to 30 minutes with a diluted solution of 50 to 100 mL or more as an infusion solution.
      • ㆍ For intramuscular injection, inject deeply.
    • 1. Adults
      0.5 to 3 g (titer) of a mixture of sodium ampicillin and sodium sulbactam is administered intravenously or intramuscularly 3 to 4 times daily. The maximum daily dose is 4 g (titer) of sulbactam.
    Severity of infectious diseaseDaily dose (ampicillin sodium titer ＋ sulbactam sodium titer)
    mild 1.5~3g(1 ＋ 0.5 ~ 2＋1)
    moderate ~6g(4 ＋ 2)
    severe ~12g(8 ＋ 4)


    • 2. Newborn, infant, and pediatric use
      Administration dose is 60~150 mg/kg/day in divided in 3 to 4 doses In the case of newborns, especially premature infants, it is administered in two divided doses (at 12-hour intervals) for one week after birth.

    • 3. In patients with impairment of renal function (CrCl < 30mL/min), it should be administrated less frequently.

    • 4. Prophylaxis of postoperative infection in orthopaedic surgery : 1.5g to 3g by IV or IM routes at the time of induction of anesthesia. Administer 3 to 4 times more if necessary.
    • For intravenous or intramuscular injection, it is dissolved with distilled water for injection, normal saline solution for injection, or glucose injection solution and inject slowly over at least 3 minutes.
    titer(g)Final concentration (mg/mL)
    Total dose (g) (sulbactam/ampicillin) Diluted solution volume (mL)(sulbactam/ampicillin)
    ① 0.75 (0.25/0.5) 1.6 375(125/250)
    ② 1.5 (0.5/1.0) 3.2 375(125/250)

Storage and handling

  • Hermetically sealed container, keep at room temperature
  • 310 Pangyo-ro, Bundang-gu, Seongnam-si, Gyeonggi-do
    463-400 Korea [13494]
  • Copyright(c) SK chemicals. All Rights Reserved.

Ethical Management

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