SK chemicals Site ManagerRanking 1 in the International Index of Erectile Function (IIEF EF)!
- A challenge to normalization of erectile function by fundamentally treating erectile dysfunctions
- Minimization of existing side effects such as color sense troubles, etc. with high selectivity
- SK chemicals, proving that it is a representative enterprise for development of new drugs, with its 3rd development of new drugs
A new drug for treating erectile dysfunctions with minimization of side effects of existing erectile dysfunction treatment drugs while showing the strongest erectile effect in the world has been born by our research team

| SK chemicals(CEO, Chang-Geun Kim) has developed Mvix (mirodenafil 2HCL 100mg), a erectile dysfunction drug, to minimize side effects that have been pointed out as a disadvantage of existing erectile dysfunction treatment drugs while maximizing male’s erectile function, as the No.13 of domestic new drugs, and has acquired [product item license for manufacturing drugs] from KFDA. Mvix, a new drug for treating erectile dysfunctions, was started to be developed in the past 1998 jointly by SK chemicals and In2Gen, a bio-venture, and has successfully finished pre-clinical tests in 2004, 1st phase clinical tests (Covance in UK) in 2004, 2nd phase clinical tests in March 2005 and 3rd phase clinical tests in March 2006, by investing 15 billion won of development costs.
Jae-Seung Baek, a professor at Seoul National University who had led the clinical tests of Mvix, said, “according to the results of 3rd phase clinical tests conducted to 223 persons at 15 general hospitals in Korea such as Seoul National University Hospital, etc., Mvix of 100mg has recorded insertion rate into the vagina 91.95%, intercourse completion rate 73.20%, normal erectile function recovery rate 62.16% and overall satisfaction rate 89.04%, and has remarkably improved overall satisfaction levels toward life along with satisfaction levels of sex life, relationships with partners and home life.”
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Especially, Mvix has acquired a high score of 25.7 points out of a possible 30 in the measurement of the international index of erectile functions (IIEF EF), an international index to indicate the efficacy of erectile dysfunction treatment drugs, so as to obtain the highest score in history by putting existing drugs out of the way. (26 or more points of IIEF EF may be in the [normal erectile function] level)
Besides, as an effect of fundamental erectile dysfunction treatment rather than temporary symptom improvement, among the patient group that had freely taken it for more than 12 weeks, the normal erectile function recovery rate reached 46%, an excellent effect.
Meanwhile, in the clinical test by Covance in UK and the efficacy examination by MDS Phama in U.S., Mvix showed only a little face flushing and headache in terms of safety so as to report remarkably lower side effect occurrence rate than existing competing products and report no heart related side effects, which is more excellent safety than existing erectile dysfunction treatment drugs.
Mvix less suppresses PDE-1 and PDE-6 due to high selectivity to PDE-5 as compared with other PDE-5 starch blockers such as Viagra, etc., so as to show less headache, which is a general side effect of existing erectile dysfunction treatment drug, and report no color sense troubles.
Having been 33.3 billion won in 2001, the entire market scale of domestic erectile dysfunction treatment drugs was 64 billion won in 2004, 70.5 billion won in 2005 and 77 billion won (36.5 billion won for Viagra, 22.5 billion won for Cialis, 9.6 billion won for Zydena, etc./IMS data) in 2006, which recorded a high growth rate of over 10% a year, and Mvix is expecting about 10 billion won of sales in 2008.
SK chemicals has completed registration of Chinese trade mark name(愛比獅 Aibishi) in order to advance into the Chinese erectile dysfunction treatment drug markets of 450 billion won(4 billion RMB) scales, is proceeding with local marketing through the SK Pharma Beijing(Beijing, Tianjin, Shanghai), an affiliate of SK chemicals, and is expecting local sales of over 10 billion won from 2009 when the advancement of Mvix becomes serious.
Meanwhile, with the development of Mvix at this time, SK chemicals has realized a heroic deed to notify the excellence of our life science and technology to the inside and outside of the country as well as reconfirm the position of Korea’s life science R&D as the eldest son by succeeding in the 3rd independent development of new drugs for the first time in Korea, following the success in the development of an anti-cancer medicine [Sunpla], the No.1 new drug in Korea, in 1999 and the development of an arthritis treatment drug[Joins], the No.1 new natural drug in Korea, in 2001.
Seung-Gwon Shin, CEO in the life science part of SK chemicals, said, “Mvix was developed with a view to a happy drug to satisfy both of efficacy and safety” and “it will be going to pursue real home happiness through couple love by taking a position as a pronoun of home erectile dysfunction treatment drugs in the overseas markets as well as domestic markets.
Currently, Mvix is securing intellectual property rights by registering and applying material patents to 38 nations in the world such as United States, EU, China, Japan, etc. and is promoting technology exports to major nations such as China, etc. as well as selling it in domestic markets. <The end>
⊙ Seong-Woo Kim, a manger of press PR of SK chemicals( H: 011-248-5308 ), / Joon-Ho Jung, an assistant manager(H:016-581-9717)
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1. Interpretation of terminology
The International Index of Erectile Function(IIEF)
The international index of erectile function(IIEF) is a self-evaluation method to enable composite measurement of sexual functions being used most basically to evaluate male’s sexual functions by describing 5 kinds of domains(erectile function, orgasmic function, sexual desire, intercourse satisfaction and overall satisfaction) related to male’s sexual functions.
IIEF is being promoted as a major evaluation variable to diagnostically evaluate event a serious illness of ED as well as a clinical test of ED(erectile dysfunction) in the world. IIEF was first developed in association with a clinical test program of sildenafil (Vigra) and is currently being adopted as a ‘gold standard’ measurement method to evaluate validity in the clinical test of ED. Translated into 32 languages including Korean, IIEF was proved in terms of reliability and appropriateness so as to be used as a major validity evaluation variable in over 50 clinical tests.
IIEF can measure up to psychological part of sexual functions, is being continuously adopted in random clinical tests of sildenafil and other ED treatment drugs, and is widely used to classify the seriousness of ED and the prevalence rate of illness, according to the reports in various papers. Besides, this shows consistent and firm treatment reactions in the research proceeded with in various etiological small groups as well as United States, Europe and Asia. Like this, IIEF is an evaluation method to show high sensitivity and specificity satisfying the psychological evaluation criteria of ED clinical tests reliably and appropriately.
Covance in UK
This is the best multi-national clinical test agency (Contract Research Organization: CRO) in the world to professionally execute all steps of clinical tests during development of new drugs for others. This is officially acknowledged in terms of its public trust by EMEA and FDA and is providing global services by operating its head office at Princeton city, New Jersey, and by operating multiple pre-clinical laboratories and clinical test clinics in the major regions of United States and Europe. This has been conducting pre-clinical and clinical tests by participating in the worldwide development processes of new drugs and has successfully conducted tests from pre-clinical safety tests to 1st, 2nd and 3rd phase clinical tests of Vigra, especially a market leader of ED treatment drugs.
MDS Pharma in United States
As one of the biggest CROs(CRO Contract Research Organization) in the world, this is a new drug development service provider with annual revenue exceeding 2 trillion won and with 70 or more branches in the world. This provides a comprehensive global new drug development service covering things from excavation to development of new drugs by conducting tests from drug search, efficacy test and pre-clinical safety evaluation to 1st, 2nd, 3rd and 4th phase clinical tests. Provided with the best facilities and research teams, this has been acknowledged in terms of reliability of test results by the relevant institutions in United States, Europe and Japan and has conducted pre-clinical and clinical tests of worldwide new drugs.
Bio-availability
This is a ratio to be absorbed into body blood.
Color sense troubles
Color weakness or color blindness being not able to identify colors. Color sense troubles being not able to identify between red and green are most often.
愛比獅(Aibishi)
This is a Chinese brand name of Mvix meaning ‘stronger love than lions’, which symbolizes [a male with self-confidence like a lion, the king of beasts leading multiple female lion groups].
Mvix brand name
Mvix has a meaning of [an ED treatment drug to build male’s self-confidence bigger] by combining alphabet [M] meaning male’s symbolic words such as Man, Macho, Male, Muscle, etc. and [vix] borrowing the pronunciation of Bigs, Victorys, etc. and has been developed based on English brands with a view to global advancement.
Mvix logo
Mvix logos are expressed with visual symbolization of the use and efficacy of new drugs by utilizing alphabet capital letter [M] and reverse triangular points symbolizing males or products, as [Motif], so as to appeal to the emotion of consumers.

A Mvix logo to show hot efficacy between knees
2. History of the life science part of SK chemicals
1988. 06 Establishment of SK Pharmaceutical
1989. 07 Establishment of Life Science Research Center
1992. 02 Sales of blood circulation improvement drugs made from ginkgo leaves [Ginexin]
1994. 00 Sales of gastric and duodenal ulcer treatment drugs [Omed]
1996. 04 Sales of arthritis treatment patch [Trast] for the first time in the world
1999. 07 Development of the 3rd generation platinum plated anti-cancer drug [Sunpla] for the first time in the world, the No.1 new drug in Korea
1999. 00 Export of [Omed], a drug perfectly made in Korea, to EU for the first time
2000. 07 Establishment of [In2Gen], a bio venture
2001. 03 Takeover of Dongshin Pharmaceutical
2001. 07 Acquisition of product item license for arthritis treatment drugs [Joins], the No.1 new natural drug in Korea
2004. 05 Conclusion of contracts for exporting gastric ulcer treatment drugs ‘Omed’ to 7 Middle East countries, with Pharmaco company
2005. 04 Merger of SK Pharmaceutical, and reorganization of it into the life science part of SK chemicals
2005. 11 Establishment of SK Pharma Beijiing
2006. 11 Merger of Dongshin Pharmaceutical
2007. 07 Acquisition of product item license for a ED treatment drug [Mvix], the No.14? new drug in Korea.